| Product Name | BTR1 Polyclonal Antibody |
|---|---|
| Description | This gene encodes a voltage-regulated, electrogenic sodium-coupled borate cotransporter that is essential for borate homeostasis, cell growth and cell proliferation. Mutations in this gene have been associated with a number of endothelial corneal dystrophies including recessive corneal endothelial dystrophy 2, corneal dystrophy and perceptive deafness, and Fuchs endothelial corneal dystrophy. Multiple transcript variants encoding different isoforms have been described.SLC4A11 (Solute Carrier Family 4 Member 11) is a Protein Coding gene. Diseases associated with SLC4A11 include Corneal Endothelial Dystrophy 2, Autosomal Recessive and Corneal Endothelial Dystrophy And Perceptive Deafness. GO annotations related to this gene include transporter activity and symporter activity. An important paralog of this gene is SLC4A3. |
| Synonyms | SLC4A11; BTR1; Sodium bicarbonate transporter-like protein 11; Bicarbonate transporter-related protein 1; Sodium borate cotransporter 1; NaBC1; Solute carrier family 4 member 11 |
| Host | Rabbit |
| Immunogen | Synthesized peptide derived from the Internal region of human BTR1 |
| Isotype | IgG |
| Reactivity | Human |
| Applications | ELISA, WB |
| Form | PBS with 0.02% sodium azide,0.5% BSA and 50% glycerol pH 7.4. |
| Uniprot | Q8NBS3 |
| Background | This gene encodes a voltage-regulated, electrogenic sodium-coupled borate cotransporter that is essential for borate homeostasis, cell growth and cell proliferation. Mutations in this gene have been associated with a number of endothelial corneal dystrophies including recessive corneal endothelial dystrophy 2, corneal dystrophy and perceptive deafness, and Fuchs endothelial corneal dystrophy. Multiple transcript variants encoding different isoforms have been described.SLC4A11 (Solute Carrier Family 4 Member 11) is a Protein Coding gene. Diseases associated with SLC4A11 include Corneal Endothelial Dystrophy 2, Autosomal Recessive and Corneal Endothelial Dystrophy And Perceptive Deafness. GO annotations related to this gene include transporter activity and symporter activity. An important paralog of this gene is SLC4A3. |
| Supplier | Elabscience |
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