| Product Name | c-MPL/TPOR, Mouse, ELISA Kit |
|---|---|
| Description | Thrombopoietin promotes the growth and differentiation (proliferation) ofmegakaryocytes which produce platelets. TPOR (Thrombopoietin receptor), whichis also called c-MPL (Myeloproliferative leukemia protein) or CD110, is a receptorfor thrombopoietin. And it is suggested that TPOR may also play a role in themaintenance of hematopoietic stem cells, which are stem cells located within thebone marrow that have the potential to develop into red blood cells, white blood cells, mega karyocytes and platelets. This receptor is activated when thrombopoietin protein binds to it, and the activated receptor stimulates a signaling pathway called the JAK/STAT pathway, which transmits signals from outside the cell to the cell's nucleus and is important for controlling the production of blood cells. This ELISA kit can measure concentration of mouse soluble c-MPL/TPOR in serum or cell culture supernatant. This kit is a solid phase sandwich ELISA using 2 kinds of highly specific antibodies. Tetra Methyl Benzidine (TMB) is used as a coloring agent (Chromogen). The strength of coloring is proportional to the quantities of Mouse soluble c-MPL/TPOR. |
| Reactivity | Mouse |
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