C5AR1 Antibody

Category: Antibodies
Catalog
CSB-PA003996LA01HU
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Product Name C5AR1 Antibody
Description Rabbit polyclonal antibody to C5AR1
Synonyms ANAPHYLATOXIN RECEPTOR antibody; C5a anaphylatoxin chemotactic receptor antibody; C5a anaphylatoxin receptor antibody; C5A antibody; C5a ligand antibody; C5a-R antibody; C5aR antibody; C5AR_HUMAN antibody; c5ar1 antibody; C5R1 antibody; CD88 antibody; CD88 antigen antibody; Complement component 5 receptor 1 antibody; Complement component 5 receptor 2 antibody; Complement component 5a receptor 1 antibody
Host Rabbit
Clonality Polyclonal
Conjugate Unconjugated
Immunogen Recombinant human C5a anaphylatoxin chemotactic receptor 1 protein (1-36AA)
Isotype IgG
Target C5AR1
Reactivity Human
Applications ELISA, IF, WB
Form Liquid
Diluent Buffer Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Uniprot P21730
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Background Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a (PubMed:1847994, PubMed:8182049, PubMed:7622471, PubMed:9553099, PubMed:10636859, PubMed:15153520). The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events (PubMed:8182049, PubMed:7622471, PubMed:9553099). Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production (PubMed:10636859, PubMed:15153520).
Supplier Cusabio

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