| Product Name | C8 _ Polyclonal Antibody |
|---|---|
| Description | C8B (Complement C8 Beta Chain) is a Protein Coding gene. Diseases associated with C8B include C8 Deficiency, Type Ii and Immunodeficiency Due To A Late Component Of Complement Deficiency. Among its related pathways are Complement Pathway and Innate Immune System. GO annotations related to this gene include protein complex binding. An important paralog of this gene is C8A.This gene encodes one of the three subunits of the complement component 8 (C8) protein. C8 is composed of equimolar amounts of alpha, beta and gamma subunits, which are encoded by three separate genes. C8 is one component of the membrane attack complex, which mediates cell lysis, and it initiates membrane penetration of the complex. This protein mediates the interaction of C8 with the C5b-7 membrane attack complex precursor. In humans deficiency of this protein is associated with increased risk of meningococcal infections. Alternative splicing results in multiple transcript variants. |
| Synonyms | Complement component C8 beta chain (Complement component 8 subunit beta) |
| Host | Rabbit |
| Immunogen | Synthesized peptide derived from C8 _ |
| Isotype | IgG |
| Reactivity | Human, Rat |
| Applications | ELISA, WB |
| Form | PBS with 0.02% sodium azide,0.5% BSA and 50% glycerol pH 7.4. |
| Uniprot | P07358 |
| Background | C8B (Complement C8 Beta Chain) is a Protein Coding gene. Diseases associated with C8B include C8 Deficiency, Type Ii and Immunodeficiency Due To A Late Component Of Complement Deficiency. Among its related pathways are Complement Pathway and Innate Immune System. GO annotations related to this gene include protein complex binding. An important paralog of this gene is C8A.This gene encodes one of the three subunits of the complement component 8 (C8) protein. C8 is composed of equimolar amounts of alpha, beta and gamma subunits, which are encoded by three separate genes. C8 is one component of the membrane attack complex, which mediates cell lysis, and it initiates membrane penetration of the complex. This protein mediates the interaction of C8 with the C5b-7 membrane attack complex precursor. In humans deficiency of this protein is associated with increased risk of meningococcal infections. Alternative splicing results in multiple transcript variants. |
| Supplier | Elabscience |
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