| Product Name | C9, 22-559aa Human |
|---|---|
| Description | C9 is the final component of the complement system. It participates in the formation of the Membrane Attack Complex (MAC). The MAC assembles on bacterial membranes to form a pore, permitting disruption of bacterial membrane organization. Mutations in this gene cause component C9 deficiency. Recombinant human C9 protein, fused to His-tag at N-terminus, was expressed in E.coli . |
| Synonyms | Complement component C9 precursor, Complement component 9 |
| Host | E. coli |
| Molecular Weight | 10.7 kDa (101aa) confirmed by MALDI-TOF |
| Amino Acid Sequence | MGSSHHHHHH SSGLVPRGSH MGSQYTTSYD PELTESSGSA SHIDCRMSPW SEWSQCDPCL RQMFRSRSIE VFGQFNGKRC TDAVGDRRQC VPTEPCEDAE DDCGNDFQCS TGRCIKMRLR CNGDNDCGDF SDEDDCESEP RPPCRDRVVE ESELARTAGY GINILGMDPL STPFDNEFYN GLCNRDRDGN TLTYYRRPWN VASLIYETKG EKNFRTEHYE EQIEAFKSII QEKTSNFNAA ISLKFTPTET NKAEQCCEET ASSISLHGKG SFRFSYSKNE TYQLFLSYSS KKEKMFLHVK GEIHLGRFVM RNRDVVLTTT FVDDIKALPT TYEKGEYFAF LETYGTHYSS SGSLGGLYEL IYVLDKASMK RKGVELKDIK RCLGYHLDVS LAFSEISVGA EFNKDDCVKR GEGRAVNITS ENLIDDVVSL IRGGTRKYAF ELKEKLLRGT VIDVTDFVNW ASSINDAPVL ISQKLSPIYN LVPVKMKNAH LKKQNLERAI EDYINEFSVR KCHTCQNGGT VILMDGKCLC ACPFKFEGIA CEISKQKISE GLPALEFPNE K |
| Tag | His-tag |
| Reactivity | Human |
| Applications | SDS-PAGE |
| Form | Liquid, in 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 30% glycerol, 1mM DTT |
| Concentration | 0.25 mg/ml (determined by Bradford assay) |
| Purity | > 80% by SDS-PAGE |
| Storage | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -2°C or -7°C. Avoid repeated freezing and thawing cycles. |
| References | Lint TF, Zeitz HJ, et al. (1980) J. Immunol. 125 (5): 2252–7 |
| Background | C9 is the final component of the complement system. It participates in the formation of the Membrane Attack Complex (MAC). The MAC assembles on bacterial membranes to form a pore, permitting disruption of bacterial membrane organization. Mutations in this gene cause component C9 deficiency. Recombinant human C9 protein, fused to His-tag at N-terminus, was expressed in E.coli . |
| Supplier | ARP |
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