| Product Name | CAMK2G/CAMK2B Antibody |
|---|---|
| Description | Rabbit polyclonal antibody to CAMK2G |
| Synonyms | Calcium/calmodulin-dependent protein kinase type II gamma chain; EC 2.7.11.17; CaM-kinase II gamma chain; CaM kinase II subunit gamma; CaMK-II subunit gamma |
| Host | Rabbit |
| Clonality | Polyclonal |
| Conjugate | Unconjugated |
| Immunogen | Synthesized peptide derived from C-terminal of human CaMK2_/_. |
| Isotype | IgG |
| Target | CAMK2G/CAMK2B |
| Reactivity | Human, Mouse, Rat |
| Applications | ELISA, WB |
| Form | liquid |
| Diluent Buffer | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Uniprot | Q13555/Q13554 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Background |
Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca2+/calmodulin-binding and autophosphorylation, and is involved in sarcoplsamic reticulum Ca2+ transport in skeletal muscle and may function in dendritic spine and synapse formation and neuronal plasticity. In slow-twitch muscles, is involved in regulation of sarcoplasmic reticulum (SR) Ca2+ transport and in fast-twitch muscle participates in the control of Ca2+ release from the SR through phosphorylation of the ryanodine receptor-coupling factor triadin. In neurons, may participate in the promotion of dendritic spine and synapse formation and maintenance of synaptic plasticity which enables long-term potentiation (LTP) and hippocampus-dependent learning. Deloukas P., Nature 429:375-381(2004). Breen M.A., Biochem. Biophys. Res. Commun. 236:473-478(1997). Tombes R.M., Biochim. Biophys. Acta 1355:281-292(1997). |
| Supplier | Cusabio |
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