| Product Name | CARD8 Antibody |
|---|---|
| Description | Rabbit polyclonal antibody to CARD8 |
| Synonyms | Apoptotic protein NDPP 1 antibody; Apoptotic protein NDPP1 antibody; CARD 8 antibody; CARD inhibitor of NF kappa B activating ligand antibody; CARD inhibitor of NF kappaB activating ligand antibody; CARD inhibitor of NF kappaB activating ligands antibody; CARD-inhibitor of NF-kappa-B-activating ligand antibody; CARD8 antibody; CARD8_HUMAN antibody; CARDINAL antibody; Caspase recruitment domain containing protein 8 antibody; Caspase recruitment domain family member 8 antibody; Caspase recruitment domain protein 8 antibody; Caspase recruitment domain-containing protein 8 antibody; DACAR antibody; Dakar antibody; DKFZp779L0366 antibody; FLJ18119 antibody; FLJ18121 antibody; KIAA0955 antibody; MGC57162 antibody; NDPP 1 antibody; NDPP antibody; NDPP1 antibody; TUCAN antibody; Tumor up regulated CARD containing antagonist of CASP9 antibody; Tumor up regulated CARD containing antagonist of caspase 9 antibody; Tumor up-regulated CARD-containing antagonist of CASP9 antibody; tumor up-regulated CARD-containing antagonist of caspase nine antibody; Tumor upregulated CARD containing antagonist of CASP9 antibody |
| Host | Rabbit |
| Clonality | Polyclonal |
| Conjugate | Unconjugated |
| Immunogen | Fusion protein of human CARD8 |
| Isotype | IgG |
| Target | CARD8 |
| Reactivity | Human |
| Applications | ELISA, IHC |
| Form | Liquid |
| Diluent Buffer | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Uniprot | Q9Y2G2 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Background | The protein encoded by this gene belongs to the caspase recruitment domain (CARD)-containing family of proteins, which are involved in pathways leading to activation of caspases or nuclear factor kappa-B (NFKB). This protein may be a component of the inflammasome, a protein complex that plays a role in the activation of proinflammatory caspases. It is thought that this protein acts as an adaptor molecule that negatively regulates NFKB activation, CASP1-dependent IL1B secretion, and apoptosis. Polymorphisms in this gene may be associated with a susceptibility to rheumatoid arthritis. |
| Supplier | Cusabio |
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