| Product Name | Caspase 8 Monoclonal Antibody |
|---|---|
| Description | Caspase 8,also named as MCH5,MACH,FLICE,and CAP4,belongs to the peptidase C14A family. It may participate in the GZMB apoptotic pathways and functions as an upstream regulator in a-bisabolol-induced apoptosis. Caspase 8 catalyzes an essential intermediate step in the ubiquitination and proteasome-mediated degradation of IRF3. It may control diabetic embryopathy-associated apoptosis via Caspase 8 is expressed as nine isoforms by alternative splicing with the molecular mass from 26 kDa to 62 kDa. Caspase 8 Monoclonal Antibody can recognize pro- and cleaved-caspase 8. |
| Synonyms | Apoptotic cysteine protease,Apoptotic protease Mch 5,Casp 8,CASP8,Caspase 8,Caspase 8/p18,Caspase8,FADD like ICE,FLICE,ICE like apoptotic protease 5,MACH,MCH5 |
| Host | Mouse |
| Clone | 98 |
| Immunogen | Fusion protein of Caspase 8 |
| Isotype | IgG2b |
| Reactivity | Human, Mouse |
| Applications | ELISA, IF, IHC, WB |
| Form | PBS with 0.02% sodium azide, 50% glycerol, PH7.3 |
| Uniprot | Q14790 |
| Background | Caspase 8,also named as MCH5,MACH,FLICE,and CAP4,belongs to the peptidase C14A family. It may participate in the GZMB apoptotic pathways and functions as an upstream regulator in a-bisabolol-induced apoptosis. Caspase 8 catalyzes an essential intermediate step in the ubiquitination and proteasome-mediated degradation of IRF3. It may control diabetic embryopathy-associated apoptosis via Caspase 8 is expressed as nine isoforms by alternative splicing with the molecular mass from 26 kDa to 62 kDa. Caspase 8 Monoclonal Antibody can recognize pro- and cleaved-caspase 8. |
| Supplier | Elabscience |
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