| Product Name | Caspase 9/p35/p10 Monoclonal Antibody |
|---|---|
| Description | Caspase 9,apoptosis-related cysteine protease (CASP9,synonyms: MCH6,APAF3,APAF-3,ICE-LAP6,CASPASE-9c)is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits,large and small,that dimerize to form the active enzyme. Capase 9 is processed by caspase APAF1; this step is thought to be one of the earliest in the caspase activation cascade. |
| Synonyms | APAF 3,APAF3,Apoptotic protease Mch 6,CASP 9,CASP9,Caspase 9,Caspase 9/p35/p10,CASPASE 9c,Caspase9,Caspase-9,ICE LAP6,ICE like apoptotic protease 6,MCH6 |
| Host | Mouse |
| Clone | 34 |
| Immunogen | Fusion protein of Caspase 9/p35/p10 |
| Isotype | IgG2b |
| Reactivity | Human, Mouse, Rat |
| Applications | ELISA, IF, IHC, WB |
| Form | PBS with 0.02% sodium azide, 50% glycerol, PH7.3 |
| Uniprot | P55211 |
| Background | Caspase 9,apoptosis-related cysteine protease (CASP9,synonyms: MCH6,APAF3,APAF-3,ICE-LAP6,CASPASE-9c)is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits,large and small,that dimerize to form the active enzyme. Capase 9 is processed by caspase APAF1; this step is thought to be one of the earliest in the caspase activation cascade. |
| Supplier | Elabscience |
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