| Product Name | Cat Peripherin-2 (PRPH2) ELISA Kit |
|---|---|
| Description | Peripherin 2 is a cell surface glycoprotein found in the outer segment of both rod and cone photoreceptor cells. It is located in the rim regions of the flattened disks that contain rhodopsin, which is the protein that is responsible for initiation of visual phototransduction upon reception of light. Peripherin 2 may function as an adhesion molecule involved in stabilization and compaction of outer segment disks or in the maintenance of the curvature of the rim. This protein is essential for disk morphogenesis. Defects in this gene are associated with both central and peripheral retinal degenerations. Some of the various phenotypically different disorders are autosomal dominant retinitis pigmentosa, progressive macular degeneration, macular dystrophy and retinitis pigmentosa digenic. This assay has high sensitivity and excellent specificity for detection of Cat PRPH2. No significant cross-reactivity or interference between Cat PRPH2 and analogues was observed. |
| Synonyms | AOFMD, AVMD, CACD2, PRPH, RDS, RP7, TSPAN22, rd2, peripherin 2|peripherin 2, homolog of mouse|peripherin, photoreceptor type|retinal peripherin|tetraspanin-22 |
| Method | Sandwich ELISA |
| Detection Range | Request Information |
| Sensitivity | Request Information |
| Reactivity | Feline |
| Sample Types | Serum, Plasma, Other biological fluids. |
| Background | Peripherin 2 is a cell surface glycoprotein found in the outer segment of both rod and cone photoreceptor cells. It is located in the rim regions of the flattened disks that contain rhodopsin, which is the protein that is responsible for initiation of visual phototransduction upon reception of light. Peripherin 2 may function as an adhesion molecule involved in stabilization and compaction of outer segment disks or in the maintenance of the curvature of the rim. This protein is essential for disk morphogenesis. Defects in this gene are associated with both central and peripheral retinal degenerations. Some of the various phenotypically different disorders are autosomal dominant retinitis pigmentosa, progressive macular degeneration, macular dystrophy and retinitis pigmentosa digenic. |
| Supplier | Abebio |
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