| Product Name | CATH-2 (chicken) |
|---|---|
| Description | CATH-2 (chicken) is one of four cathelicidins which have been identified in chickens. Cathelicidins constitute a family of host defense peptides (HDPs) and play an important role during the innate immune response and CATH-2 displays strong antimicrobial activities against many different pathogens including gram-positive and gram-negative bacteria and fungi. In addition, CATH-2 has been shown to have immunomodulatory capacities. |
| Synonyms | Chicken cathelicidin-2 |
| Molecular Weight | 3206.9 Da |
| Target | Antibacterials |
| Amino Acid Sequence | RFGRFLRKIRRFRPKVTITIQGSARF-NH2 |
| Form | Freeze dried solid |
| Purity | >95% by HPLC |
| Storage | Store desiccated, frozen and in the dark |
| Notes | Modifications: C terminal amide |
| References |
Cuperus et al (2013) Avian host defense peptides. Develop. Comp. Immunol. 41(3) 352 PMID: 24583933Ordonez et al (2014) Fungicidal Mechanisms of Cathelicidins LL-37 and CATH-2 Revealed by Live-Cell Imaging. Antimicrob. Agents Chemother. 58(4) 2240 PMID: 24492359Scheenstra et al (2019) Cathelicidins PMAP-36, LL-37 and CATH-2 are similar peptides with different modes of action. Sci Rep 9 4780 PMID: 30886247 Related areasAll antimicrobial peptides >All antifungal agents >All immunology research categories > |
| Supplier | Isca Biochemicals Limited |
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