| Product Name | Caveolin-1 scaffolding domain peptide |
|---|---|
| Description |
Caveolin-1 scaffolding domain peptide is amino acids 82–101 of caveolin-1, a structural cytoplasmic membrane protein involved in the formation and function of caveolae. Caveolin-1 scaffolding domain peptide can reverse aging associated fibrosis, microvascular leakage, and organ dysfunction in the heart, kidneys, and brain of mice through a mechanism that involves the suppression of the activity of multiple tyrosine kinases, reducing age related microvascular leakage and interstitial fibrosis to the levels of healthy, young mice. |
| Synonyms | CSD |
| Molecular Weight | 2516.88 Da |
| Target | Protein-protein interactions,Kinases |
| Amino Acid Sequence | DGIWKASFTTFTVTKYWFYR-NH2 |
| Form | Freeze dried solid |
| Purity | >95% by hplc |
| Storage | Store dry, frozen and in the dark |
| Notes | Modifications: C terminal amide |
| References |
Kuppuswamy et al (2021) The Caveolin-1 Scaffolding Domain Peptide Reverses Aging-Associated Deleterious Changes in Multiple Organs. J Pharmacol Exp Ther. 378(1) 1 PMID: 33879542 Related areasAll peptides >All protein-protein interaction modulators >All kinase modulators >All cardiovascular research categories > |
| Supplier | Isca Biochemicals Limited |
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