CBLB Monoclonal Antibody

Category: Antibodies
Catalog
E-AB-27652
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Product Name CBLB Monoclonal Antibody
Description CBLB(E3 ubiquitin-protein ligase CBL-B) is also known as RNF56 and plays a necessary role to prevent the inappropriate activation of NF-B in response to lipopolysaccharide and to polymicrobial sepsis. CBLB can be phosphorylated on tyrosine and serine residues upon TCR or BCR activation,and upon various types of cell stimulation.. It also has a crucial role in the prevention of chronic inflammation and autoimmunity. This protein has 3 isoforms produced by alternative splicing.
Synonyms CBLB,DKFZp686J10223,DKFZp779A0729,DKFZp779F1443,FLJ36865,FLJ41152,Nbla00127,RING finger protein 56,RNF56,SH3 binding protein CBL B
Host Mouse
Clone 2D3A2
Immunogen Fusion Protein of CBLB
Isotype IgG3
Reactivity Human, Mouse, Rat
Applications ELISA, IF, IHC, WB
Form PBS with 0.02% sodium azide, 50% glycerol, PH7.3
Uniprot Q13191
Background CBLB(E3 ubiquitin-protein ligase CBL-B) is also known as RNF56 and plays a necessary role to prevent the inappropriate activation of NF-B in response to lipopolysaccharide and to polymicrobial sepsis. CBLB can be phosphorylated on tyrosine and serine residues upon TCR or BCR activation,and upon various types of cell stimulation.. It also has a crucial role in the prevention of chronic inflammation and autoimmunity. This protein has 3 isoforms produced by alternative splicing.
Supplier Elabscience

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