| Product Name | CCNL1 Antibody |
|---|---|
| Description | Rabbit polyclonal antibody to CCNL1 |
| Synonyms | CCNL1 antibody; BM-001 antibody; UNQ530/PRO1073 antibody; Cyclin-L1 antibody; Cyclin-L antibody |
| Host | Rabbit |
| Clonality | Polyclonal |
| Conjugate | Unconjugated |
| Immunogen | Synthesized peptide derived from human Cyclin-L1. |
| Isotype | IgG |
| Target | CCNL1 |
| Reactivity | Human, Mouse, Rat |
| Applications | ELISA, IHC, WB |
| Form | liquid |
| Diluent Buffer | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Uniprot | Q9UK58 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Background |
Transcriptional regulator which participates in regulating the pre-mRNA splicing process. Seems to be involved in the regulation of RNA polymerase II (pol II). Functions in association with cyclin-dependent kinases (CDKs) and has a role in the second step of splicing. May be a candidate proto-oncogene in head and neck squamous cell carcinomas (HNSCC). Inhibited by the CDK-specific inhibitor p21. A. Hamid Boulares, J. Biol. Chem., Aug 1999; 274: 22932. Alessandra Pagano, Am J Physiol Lung Cell Mol Physiol, Jun 2007; 10.1152. Mi Young Kim, Genes & Dev., Sep 2005; 19: 1951 - 1967. Silke S___e, Nucleic Acids Res., Feb 2004; 32: 669 - 680. |
| Supplier | Cusabio |
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