| Product Name | CCP110 Antibody |
|---|---|
| Description | Rabbit polyclonal antibody to CCP110 |
| Synonyms | 110 kDa centrosomal protein antibody; CCP110 antibody; Centriolar coiled coil protein 110kDa antibody; Centrosomal protein 110 kDa antibody; Centrosomal protein CP110 antibody; Centrosomal protein of 110 kDa antibody; Cep110 antibody; CP110 antibody; CP110_HUMAN antibody; DKFZp781G1416 antibody; FAN antibody; KIAA0419 antibody |
| Host | Rabbit |
| Clonality | Polyclonal |
| Conjugate | Unconjugated |
| Immunogen | Recombinant human Centriolar coiled-coil protein of 110 kDa protein (1-280AA) |
| Isotype | IgG |
| Target | CCP110 |
| Reactivity | Human |
| Applications | ELISA, IHC, WB |
| Form | Liquid |
| Diluent Buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Uniprot | O43303 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Background | Necessary for centrosome duplication at different stages of procentriole formation. Acts as a key negative regulator of ciliogenesis in collaboration with CEP97 by capping the mother centriole thereby preventing cilia formation (PubMed:17719545 PubMed:17681131, PubMed:23486064). Also involved in promoting ciliogenesis. May play a role in the assembly of the mother centriole subdistal appendages (SDA) thereby effecting the fusion of recycling endosomes to basal bodies during cilia formation (By similarity). Required for correct spindle formation and has a role in regulating cytokinesis and genome stability via cooperation with CALM1 and CETN2 (PubMed:16760425). |
| Supplier | Cusabio |
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