| Product Name | CD14 Monoclonal Antibody,APC Conjugated |
|---|---|
| Description | Mouse monoclonal antibody against CD14 onjugated to APC |
| Host | Mouse |
| Clonality | Monoclonal |
| Conjugate | Unconjugated |
| Isotype | IgG1 |
| Target | CD14 |
| Reactivity | Human |
| Applications | ELISA, FC, IF |
| Form | liquid |
| Diluent Buffer | Phosphate-buffered solution, pH7.4, containing 0.09% sodium azide and 0.2% (w/v) BSA |
| Uniprot | P08571 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Background |
4AW4 reacts with CD14, a 53-55 kDa molecule. CD14 is a human high affinity cell-surface receptor for complexes of lipopolysaccharide (LPS-endotoxin) and serum LPS-binding protein (LPB). CD14 antigen has a strong presence on the surface of monocytes/macrophages, is weakly expressed on granulocytes, but not expressed by myeloid progenitor cells. CD14 functions as a receptor for endotoxin; when the monocytes become activated they release cytokines such as TNF, and up-regulate cell surface molecules including adhesion molecules.This clone is cross reactive with non-human primate. 1. Knapp, W et al., eds. (1989) Leucocyte Typing IV : White Cell Differentiation Antigens, Oxford University Press, New York. 2. Makgoba, MW et al., (1988) Nature 331: 86-88 3. Boyd. AW et al. (1989) Blood 73: 1896-1903 |
| Supplier | Cusabio |
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