| Product Name | CD164, 24-162aa, Human, Baculovirus |
|---|---|
| Description | CD164, also known as sialomucin core protein 24 isoform 1, is a type I transmembrane O-glycosylated protein that is expressed on activated perivascular and stromal cells in embryonic and tumor neovasculature. It plays a key role in hematopoiesis by facilitating the adhesion of CD34+ cells to the stroma and by negatively regulating CD34+CD38(lo/-) cell proliferation. This protein also plays an important role in prostate cancer metastasis and the infiltration of bone marrow by cancer cells. Recombinant human CD164 protein, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. |
| Synonyms | Sialomucin core protein 24 isoform 1, CD164, DFNA66, endolyn, MGC-24, MGC-24v, MUC-24 |
| Host | Virus |
| Molecular Weight |
52.5kDa (461aa) 50-70kDa (SDS-PAGE under reducing conditions) |
| Amino Acid Sequence | ADPDKNTTQH PNVTTLAPIS NVTSAPVTSL PLVTTPAPET CEGRNSCVSC FNVSVVNTTC FWIECKDESY CSHNSTVSDC QVGNTTDFCS VSTATPVPTA NSTAKPTVQP SPSTTSKTVT TSGTTNNTVT PTSQPVRKST FDHHHHHH |
| Tag | His-tag |
| Reactivity | Human |
| Applications | SDS-PAGE |
| Form | Liquid, in Phosphate Buffered Saline (pH 7.4) containing 10% glycerol. |
| Concentration | 0.5mg/ml (determined by Absorbance at 280nm) |
| Purity | > 85% by SDS-PAGE |
| Storage | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -2°C or -7°C. Avoid repeated freezing and thawing cycles. |
| References | Huang AF., et al, (2013) Mol Cancer. 12:115. Guenova E., et al, (2016) Acta Derm Venereol. 96:464-467. |
| Background | CD164, also known as sialomucin core protein 24 isoform 1, is a type I transmembrane O-glycosylated protein that is expressed on activated perivascular and stromal cells in embryonic and tumor neovasculature. It plays a key role in hematopoiesis by facilitating the adhesion of CD34+ cells to the stroma and by negatively regulating CD34+CD38(lo/-) cell proliferation. This protein also plays an important role in prostate cancer metastasis and the infiltration of bone marrow by cancer cells. Recombinant human CD164 protein, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. |
| Supplier | ARP |
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