| Product Name | CD19 Monoclonal Antibody,PE Conjugated |
|---|---|
| Description | Mouse monoclonal antibody against CD19 onjugated to PE |
| Host | Mouse |
| Clonality | Monoclonal |
| Conjugate | Unconjugated |
| Isotype | IgG1 |
| Target | CD19 |
| Reactivity | Human |
| Applications | ELISA, FC, IF |
| Form | liquid |
| Diluent Buffer | Formulation: Phosphate-buffered solution, pH 7.4, containing 0.09% sodium azide and 0.2% (w/v) BSA Application |
| Uniprot | P15391 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Background |
COC19 reacts with CD19 (B4), a 90 kDa molecule, which is expressed on approximately 5-25% of human peripheral blood lymphocytes. CD19 antigen is present on human B lymphocytes at most stages of maturation, from the earliest Ig gene rearrangement in pro-B cells to mature cell, as well as malignant B cells, but is lost on maturation to plasma cells. CD19 antibody does not react with T lymphocytes, monocytes and granulocytes. CD19 is a critical signal transduction molecule that regulates B lymphocyte development, activation and differentiation. This clone is cross reactive with non-human primate * CD19 is a key phenotyping marker of non-T cell leukemia. 1. Nadler, LM et al. (1983) J. Immunol. 131:244 2. Schlossman,SL et al., eds. (1995) Leucocyte Typing V: White Cell Differentiation Antigens, Oxford University Press, New York. 3. Tedder T. et al. (1994) Immunol Today. 15:437-442 |
| Supplier | Cusabio |
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