CD207 Antibody

Category: Antibodies
Catalog
CSB-PA204342
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Product Name CD207 Antibody
Description Rabbit polyclonal antibody to CD207
Synonyms C type lectin domain family 4 member K antibody; C-type lectin domain family 4 member K antibody; CD 207 antibody; CD207 antibody; CD207 antigen antibody; CD207 antigen; langerin antibody; CD207 molecule antibody; CLC4K_HUMAN antibody; CLEC 4K antibody; CLEC4K antibody; Langerhans cell specific c type lectin antibody; Langerin antibody; RGD1565913 antibody
Host Rabbit
Clonality Polyclonal
Conjugate Unconjugated
Immunogen Fusion protein of human CD207
Isotype IgG
Target CD207
Reactivity Human, Mouse
Applications ELISA, IHC, WB
Form Liquid
Diluent Buffer -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Uniprot Q9UJ71
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Background The protein encoded by this gene is expressed only in Langerhans cells which are immature dendritic cells of the epidermis and mucosa. It is localized in the Birbeck granules, organelles present in the cytoplasm of Langerhans cells and consisting of superimposed and zippered membranes. It is a C-type lectin with mannose binding specificity, and it has been proposed that mannose binding by this protein leads to internalization of antigen into Birbeck granules and providing access to a nonclassical antigen-processing pathway. Mutations in this gene result in Birbeck granules deficiency or loss of sugar binding activity.
Supplier Cusabio

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