| Product Name | CD23 Monoclonal Antibody |
|---|---|
| Description | CD23, the low affinity IgE (Fc-epsilon) receptor, is a glycoprotein present on a subpopulation of B lymphocytes in germinal centres, and on EBV-transformed B-lymphoblastoid cell lines. CD23 is also expressed on monocytes and dendritic cells. CD23 is primarily expressed on B cells and monocytes, including a strong expression on Epstein-Barr Virus-transformed B lymphoblasts. Anti-CD23 is a useful aid for classification of CD23-positive B-cell chronic lymphocytic leukemia/small lymphocytic lymphoma.Low-affinity receptor for immunoglobulin E (IgE) and CR2/CD21. Has essential roles in the regulation of IgE production and in the differentiation of B-cells (it is a B-cell-specific antigen). |
| Synonyms | Low affinity immunoglobulin epsilon Fc receptor,BLAST-2,C-type lectin domain family 4 member J,Fc-epsilon-RII,Immunoglobulin E-binding factor,Lymphocyte IgE receptor,CD antigen CD23 |
| Host | Mouse |
| Clone | PT0033 |
| Immunogen | Full length protein from eukaryotic expression system. |
| Isotype | IgG |
| Specificity | This antibody detects endogenous levels of CD23 |
| Reactivity | Human |
| Applications | IHC |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Uniprot | P06734 |
| Background | CD23, the low affinity IgE (Fc-epsilon) receptor, is a glycoprotein present on a subpopulation of B lymphocytes in germinal centres, and on EBV-transformed B-lymphoblastoid cell lines. CD23 is also expressed on monocytes and dendritic cells. CD23 is primarily expressed on B cells and monocytes, including a strong expression on Epstein-Barr Virus-transformed B lymphoblasts. Anti-CD23 is a useful aid for classification of CD23-positive B-cell chronic lymphocytic leukemia/small lymphocytic lymphoma.Low-affinity receptor for immunoglobulin E (IgE) and CR2/CD21. Has essential roles in the regulation of IgE production and in the differentiation of B-cells (it is a B-cell-specific antigen). |
| Supplier | Elabscience |
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