| Product Name | CD231 Polyclonal Antibody |
|---|---|
| Description | TSPAN7 (Tetraspanin 7) is a Protein Coding gene. Diseases associated with TSPAN7 include Non-Syndromic X-Linked Intellectual Disability and Miliaria Rubra. Among its related pathways are Trafficking of AMPA receptors and Transcriptional misregulation in cancer. An important paralog of this gene is ENSG00000250349.The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein and may have a role in the control of neurite outgrowth. It is known to complex with integrins. This gene is associated with X-linked mental retardation and neuropsychiatric diseases such as Huntington's chorea, fragile X syndrome and myotonic dystrophy. |
| Synonyms | Tetraspanin-7 (Tspan-7) (Cell surface glycoprotein A15) (Membrane component chromosome X surface marker 1) (T-cell acute lymphoblastic leukemia-associated antigen 1) (TALLA-1) (Transmembrane 4 superfamily member 2) (CD antigen CD231) |
| Host | Rabbit |
| Immunogen | Synthetic peptide from human protein |
| Isotype | IgG |
| Reactivity | Human, Mouse, Rat |
| Applications | ELISA, IHC |
| Form | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. |
| Uniprot | P41732 |
| Background | TSPAN7 (Tetraspanin 7) is a Protein Coding gene. Diseases associated with TSPAN7 include Non-Syndromic X-Linked Intellectual Disability and Miliaria Rubra. Among its related pathways are Trafficking of AMPA receptors and Transcriptional misregulation in cancer. An important paralog of this gene is ENSG00000250349.The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein and may have a role in the control of neurite outgrowth. It is known to complex with integrins. This gene is associated with X-linked mental retardation and neuropsychiatric diseases such as Huntington's chorea, fragile X syndrome and myotonic dystrophy. |
| Supplier | Elabscience |
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