| Product Name | CD27 Monoclonal Antibody |
|---|---|
| Description | CD27 (also known as TNFRSF7) is a type I glycoprotein expressed on some B cells and the majority of T cells,and is a member of the tumor necrosis factor (TNF) receptor family. CD27 is required for generation and long-term maintenance of T cell immunity . It is a receptor for CD70 (Cd27L). Ligation of CD27 by CD70 induces strong ubiquitination of TRAF and the activation of both canonical and non-canonical NF-kappaB pathways,as well as the JNK pathway . CD27 may also play a role in apoptosis through association with SIVA1. |
| Synonyms | CD27,CD27 antigen,CD27 molecule,CD27L receptor,S152,T cell activation antigen CD27,T14,TNFRSF7,Tp55 |
| Host | Mouse |
| Clone | 58 |
| Immunogen | Fusion protein of CD27 |
| Isotype | IgG1 |
| Reactivity | Human |
| Applications | ELISA, IHC, WB |
| Form | PBS with 0.02% sodium azide, 50% glycerol, PH7.3 |
| Uniprot | P26842 |
| Background | CD27 (also known as TNFRSF7) is a type I glycoprotein expressed on some B cells and the majority of T cells,and is a member of the tumor necrosis factor (TNF) receptor family. CD27 is required for generation and long-term maintenance of T cell immunity . It is a receptor for CD70 (Cd27L). Ligation of CD27 by CD70 induces strong ubiquitination of TRAF and the activation of both canonical and non-canonical NF-kappaB pathways,as well as the JNK pathway . CD27 may also play a role in apoptosis through association with SIVA1. |
| Supplier | Elabscience |
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