| Product Name | CD31 Monoclonal Antibody |
|---|---|
| Description | Platelet endothelial cell adhesion molecule-1 (PECAM-1,CD31) is a member of the immunoglobulin gene superfamily of cell adhesion molecules. It is highly expressed on the surface of the endothelium,making up a large portion of its intracellular junctions. PECAM-1 is also present on the surface of hematopoietic cells and immune cells including platelets,monocytes,neutrophils,natural killer cells,megakaryocytes and some types of T-cell . As well as its role in cell-cell adhesion,PECAM-1 functions as a signaling receptor,and is involved in important physiological events such as nitric oxide production,regulation of T-cell immunity and tolerance,leukocyte transendothelial migration and inflammation and angiogenesis . |
| Synonyms | CD31,EndoCAM,FLJ58394,GPIIA,PECA1,PECAM 1,PECAM1,VEC marker |
| Host | Mouse |
| Clone | 333 |
| Immunogen | Fusion protein of CD31 |
| Isotype | IgG2b |
| Reactivity | Human |
| Applications | ELISA, IF, IHC, WB |
| Form | PBS with 0.02% sodium azide, 50% glycerol, PH7.3 |
| Uniprot | P16284 |
| Background | Platelet endothelial cell adhesion molecule-1 (PECAM-1,CD31) is a member of the immunoglobulin gene superfamily of cell adhesion molecules. It is highly expressed on the surface of the endothelium,making up a large portion of its intracellular junctions. PECAM-1 is also present on the surface of hematopoietic cells and immune cells including platelets,monocytes,neutrophils,natural killer cells,megakaryocytes and some types of T-cell . As well as its role in cell-cell adhesion,PECAM-1 functions as a signaling receptor,and is involved in important physiological events such as nitric oxide production,regulation of T-cell immunity and tolerance,leukocyte transendothelial migration and inflammation and angiogenesis . |
| Supplier | Elabscience |
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