| Product Name | CD34 Monoclonal Antibody,PE Conjugated |
|---|---|
| Description | Mouse monoclonal antibody against CD34 onjugated to PE |
| Host | Mouse |
| Clonality | Monoclonal |
| Conjugate | Unconjugated |
| Isotype | IgG3 |
| Target | CD34 |
| Reactivity | Human |
| Applications | ELISA, FC, IF |
| Form | liquid |
| Diluent Buffer | Phosphate-buffered solution, pH 7.4, containing 0.09% sodium azide and 0.2% (w/v) BSA |
| Uniprot | P28906 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Background |
D34 reacts with CD34 molecule, a 105-120 kDa heavily O-glycosylated transmembrane glycoprotein expressed on hematopoietic progenitor cells, vascular endothelium and some tissue fibroblasts. The intracellular chain of the CD34 antigen is a target for phosphorylation by activated protein kinase C suggesting that CD34 may play a role in signal transduction. CD34 may play a role in adhesion of specific antigens to endothelium. Clone 43A1 belongs to the class II epitope. * CD34 mAb is useful for detection and saparation of hematopoietic stem cells 1. Schlossman, SL et al., eds. (1995) Leucocyte Typing V : White Cell Differentiation Antigens, Oxford University Press, New York. 2. Freeman SD et al., (1995) Blood 85:2005 3. Thomas R and Lipsky PE. (1994) J Immunol 153:4016 4. Nakamura Y. et al., (1994) Blood 83:1442 |
| Supplier | Cusabio |
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