| Product Name | CD3G, 23-116aa, Human, Baculovirus |
|---|---|
| Description | CD3G, also known as T-cell surface glycoprotein CD3 gamma chain, is associated on the T cell surface with a complex of protein called CD3. The protein is the CD3-gamma polypeptide, which together with CD3-epsilon, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal transduction pathways. Defects in this gene are associated with T cell immunodeficiency. Recombinant human CD3G protein, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. |
| Synonyms | T-cell surface glycoprotein CD3 gamma chain, CD3G, CD3-GAMMA, IMD17, T3G |
| Host | Virus |
| Molecular Weight |
72.3kDa (659aa) 70-150kDa (SDS-PAGE under reducing conditions.) |
| Amino Acid Sequence | ADPQSIKGNH LVKVYDYQED GSVLLTCDAE AKNITWFKDG KMIGFLTEDK KKWNLGSNAK DPRGMYQCKG SQNKSKPLQV YYRMCQNCIE LNAATISHHH HHH |
| Tag | His-tag |
| Reactivity | Human |
| Applications | SDS-PAGE |
| Form | Liquid, in Phosphate Buffered Saline (pH 7.4) containing 10% glycerol. |
| Concentration | 0.5mg/ml (determined by BCA assay) |
| Purity | > 85% by SDS-PAGE |
| Storage | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -2°C or -7°C. Avoid repeated freezing and thawing cycles. |
| References | Munoz-Ruiz M., et al. (2013) BMC Immunol. 14: 3. Gokturk B., et al. (2014) Scand J Immunol. 80:354-361. |
| Background | CD3G, also known as T-cell surface glycoprotein CD3 gamma chain, is associated on the T cell surface with a complex of protein called CD3. The protein is the CD3-gamma polypeptide, which together with CD3-epsilon, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal transduction pathways. Defects in this gene are associated with T cell immunodeficiency. Recombinant human CD3G protein, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. |
| Supplier | ARP |
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