CD46 Polyclonal Antibody

Category: Antibodies
Catalog
E-AB-14853
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Product Name CD46 Polyclonal Antibody
Description The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization.
Synonyms MCP,TLX,AHUS2,MIC10,TRA2.10
Host Rabbit
Immunogen Recombinant protein of human CD46
Isotype IgG
Reactivity Human
Applications ELISA, IHC
Form PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Uniprot P15529
Background The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization.
Supplier Elabscience

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