| Product Name | CD58, 29-215aa, Human (Denatured) |
|---|---|
| Description | CD58 is a member of the immunoglobulin superfamily. This protein is a ligand of the T lymphocyte CD2 protein, and functions in adhesion and activation of T lymphocytes. CD58 is localized to the plasma membrane. Alternatively spliced transcript variants have been described. Recombinant human CD58 protein, fused to His-tag at N-terminus, was expressed in E.coli. |
| Synonyms | CD58 molecule, CD58 molecule, ag3, LFA-3, LFA3 |
| Host | E. coli |
| Molecular Weight | 16.7 kDa (145aa) confirmed by MALDI-TOF |
| Amino Acid Sequence | MGSSHHHHHH SSGLVPRGSH MGSFSQQIYG VVYGNVTFHV PSNVPLKEVL WKKQKDKVAE LENSEFRAFS SFKNRVYLDT VSGSLTIYNL TSSDEDEYEM ESPNITDTMK FFLYVLESLP SPTLTCALTN GSIEVQCMIP EHYNSHRGLI MYSWDCPMEQ CKRNSTSIYF KMENDLPQKI QCTLSNPLFN TTSSIILTTC IPSSGHSRHR |
| Tag | His-tag |
| Reactivity | Human |
| Applications | SDS-PAGE |
| Form | Liquid, in Phosphate buffer saline (pH 7.4) containing 50% glycerol |
| Concentration | 0.25 mg/ml (determined by Bradford assay) |
| Purity | > 90% by SDS-PAGE |
| Storage | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -2°C or -7°C. Avoid repeated freezing and thawing cycles. |
| References | Challa-Malladi,M., et al. (2011) Cancer Cell 20 (6), 728-740 Patsopoulos NA, et al. (2011) Ann. Neurol. 70 (6), 897-912 |
| Background | CD58 is a member of the immunoglobulin superfamily. This protein is a ligand of the T lymphocyte CD2 protein, and functions in adhesion and activation of T lymphocytes. CD58 is localized to the plasma membrane. Alternatively spliced transcript variants have been described. Recombinant human CD58 protein, fused to His-tag at N-terminus, was expressed in E.coli. |
| Supplier | ARP |
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