| Product Name | CD66c/d Polyclonal Antibody |
|---|---|
| Description | CEACAM6 encodes a protein that belongs to the carcinoembryonic antigen (CEA) family whose members are glycosyl phosphatidyl inositol (GPI) anchored cell surface glycoproteins. Members of this family play a role in cell adhesion and are widely used as tumor markers in serum immunoassay determinations of carcinoma. This gene affects the sensitivity of tumor cells to adenovirus infection. The protein encoded by this gene acts as a receptor for adherent-invasive E. coli adhesion to the surface of ileal epithelial cells in patients with Crohn's disease. This gene is clustered with genes and pseudogenes of the cell adhesion molecules subgroup of the CEA family on chromosome 19. CEACAM6 (Carcinoembryonic Antigen Related Cell Adhesion Molecule 6) is a Protein Coding gene. Diseases associated with CEACAM6 include Crohn's Disease and Colorectal Cancer. Among its related pathways are Innate Immune System and Cell surface interactions at the vascular wall. An important paralog of this gene is CEACAM5. CEACAM3 encodes a member of the family of carcinoembryonic antigen-related cell adhesion molecules (CEACAMs), which are used by several bacterial pathogens to bind and invade host cells. The encoded transmembrane protein directs phagocytosis of several bacterial species that is dependent on the small GTPase Rac. It is thought to serve an important role in controlling human-specific pathogens by the innate immune system. Alternatively spliced transcript variants have been described. CEACAM3 (Carcinoembryonic Antigen Related Cell Adhesion Molecule 3) is a Protein Coding gene. Diseases associated with CEACAM3 include Sinonasal Undifferentiated Carcinoma and Aggressive Digital Papillary Adenocarcinoma. Among its related pathways are Innate Immune System and Cell surface interactions at the vascular wall. An important paralog of this gene is CEACAM4. |
| Synonyms | CEACAM3, CD66D, CGM1, Carcinoembryonic antigen-related cell adhesion molecule 3, Carcinoembryonic antigen CGM1, CD66d, CEACAM6, NCA, Carcinoembryonic antigen-related cell adhesion molecule 6, Non-specific crossreacting antigen, Normal cross-reacting antig |
| Host | Rabbit |
| Immunogen | Synthesized peptide derived from the Internal region of human CD66c/d. |
| Isotype | IgG |
| Reactivity | Human |
| Applications | ELISA, WB |
| Form | PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4 |
| Uniprot | P40198/P40199 |
| Background |
CEACAM6 encodes a protein that belongs to the carcinoembryonic antigen (CEA) family whose members are glycosyl phosphatidyl inositol (GPI) anchored cell surface glycoproteins. Members of this family play a role in cell adhesion and are widely used as tumor markers in serum immunoassay determinations of carcinoma. This gene affects the sensitivity of tumor cells to adenovirus infection. The protein encoded by this gene acts as a receptor for adherent-invasive E. coli adhesion to the surface of ileal epithelial cells in patients with Crohn's disease. This gene is clustered with genes and pseudogenes of the cell adhesion molecules subgroup of the CEA family on chromosome 19. CEACAM6 (Carcinoembryonic Antigen Related Cell Adhesion Molecule 6) is a Protein Coding gene. Diseases associated with CEACAM6 include Crohn's Disease and Colorectal Cancer. Among its related pathways are Innate Immune System and Cell surface interactions at the vascular wall. An important paralog of this gene is CEACAM5. CEACAM3 encodes a member of the family of carcinoembryonic antigen-related cell adhesion molecules (CEACAMs), which are used by several bacterial pathogens to bind and invade host cells. The encoded transmembrane protein directs phagocytosis of several bacterial species that is dependent on the small GTPase Rac. It is thought to serve an important role in controlling human-specific pathogens by the innate immune system. Alternatively spliced transcript variants have been described. CEACAM3 (Carcinoembryonic Antigen Related Cell Adhesion Molecule 3) is a Protein Coding gene. Diseases associated with CEACAM3 include Sinonasal Undifferentiated Carcinoma and Aggressive Digital Papillary Adenocarcinoma. Among its related pathways are Innate Immune System and Cell surface interactions at the vascular wall. An important paralog of this gene is CEACAM4. |
| Supplier | Elabscience |
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