| Product Name | CD68, 22-319aa, Human, Baculovirus |
|---|---|
| Description | CD68, also known as macrosialin, is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. It is expressed on monocytes/macrophages. It is found in cytoplasmic granules and in the cytoplasm of various non-hematopoietic tissues including liver and kidney tubules and glomeruli. CD68 is also found on the surface of macrophages, monocytes, neutrophils, basophils and large lymphocytes. Recombinant human CD68 protein, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. |
| Synonyms | Macrosialin isoform A, CD68, GP110, LAMP4, SCARD1 |
| Host | Virus |
| Molecular Weight |
23.4kDa (200aa) 28-40kDa (SDS-PAGE under reducing conditions) |
| Amino Acid Sequence | ADPNDCPHKK SATLLPSFTV TPTVTESTGT TSHRTTKSHK TTTHRTTTTG TTSHGPTTAT HNPTTTSHGN VTVHPTSNST ATSQGPSTAT HSPATTSHGN ATVHPTSNST ATSPGFTSSA HPEPPPPSPS PSPTSKETIG DYTWTNGSQP CVHLQAQIQI RVMYTTQGGG EAWGISVLNP NKTKVQGSCE GAHPHLLLSF PYGHLSFGFM QDLQQKVVYL SYMAVEYNVS FPHAAQWTFS AQNASLRDLQ APLGQSFSCS NSSIILSPAV HLDLLSLRLQ AAQLPHTGVF GQSFSCPSDR SHHHHHH |
| Tag | His-tag |
| Reactivity | Human |
| Applications | SDS-PAGE |
| Form | Liquid, in Phosphate Buffered Saline (pH 7.4) containing 10% glycerol. |
| Concentration | 0.5mg/ml (determined by Absorbance at 280nm) |
| Purity | > 95% by SDS-PAGE |
| Storage | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -2°C or -7°C. Avoid repeated freezing and thawing cycles. |
| References | Strobl H. et al., (1995) Br. J. Haematol. 90:774-782. Ogawa Y. et al., (1995) Pathol. Int. 45:698-701. |
| Background | CD68, also known as macrosialin, is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. It is expressed on monocytes/macrophages. It is found in cytoplasmic granules and in the cytoplasm of various non-hematopoietic tissues including liver and kidney tubules and glomeruli. CD68 is also found on the surface of macrophages, monocytes, neutrophils, basophils and large lymphocytes. Recombinant human CD68 protein, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. |
| Supplier | ARP |
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