| Product Name | CD70, 39-193aa, Human (Denatured) |
|---|---|
| Description | CD70 also known as CD70 antigen is cytokine that binds to CD27. This pretein plays a role in T-cell activation and induces the proliferation of costimulated T-cells and enhances the generation of cytolytic T-cells. Recombinant human CD70, fused to His-tag at N-terminus, was expressed in E.coli |
| Synonyms | CD70 antigen, CD70L, CD70LG, TNFSF7 |
| Host | E. coli |
| Molecular Weight | 56.2kDa (488aa) |
| Amino Acid Sequence | MGSSHHHHHH SSGLVPRGSH MGSQRFAQAQ QQLPLESLGW DVAELQLNHT GPQQDPRLYW QGGPALGRSF LHGPELDKGQ LRIHRDGIYM VHIQVTLAIC SSTTASRHHP TTLAVGICSP ASRSISLLRL SFHQGCTIAS QRLTPLARGD TLCTNLTGTL LPSRNTDETF FGVQWVRP |
| Tag | His-tag |
| Reactivity | Human |
| Applications | SDS-PAGE |
| Form | Liquid, in 20mM Tris-HCl (pH8.0) containing 10% glycerol |
| Concentration | 0.5mg/ml (determined by Bradford assay) |
| Purity | > 80% by SDS-PAGE |
| Storage | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -2°C or -7°C. Avoid repeated freezing and thawing cycles. |
| References | Van Damme P.et al. (2012) Proc. Natl. Acad. Sci. u.S.A. 109:12449-12454. |
| Background | CD70 also known as CD70 antigen is cytokine that binds to CD27. This pretein plays a role in T-cell activation and induces the proliferation of costimulated T-cells and enhances the generation of cytolytic T-cells. Recombinant human CD70, fused to His-tag at N-terminus, was expressed in E.coli |
| Supplier | ARP |
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