| Product Name | CD79B, 29-159aa, Human, Baculovirus |
|---|---|
| Description | CD79B, as known as B-cell antigen receptor complex-associated protein beta chain isoform 1, is B-cell-specific glycoprotein B29. It is a single-pass type 1 membrane protein containing one Ig-like V-type domain and one ITAM domain. This protein is required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR). CD79A and B proteins are required for BCR-meditated signaling and consequently for the development and activation of B lineage cells. Recombinant human CD79B, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. |
| Synonyms | B-cell antigen receptor complex-associated protein beta chain isoform 1, CD79B, AGM6, B29, IGB |
| Host | Virus |
| Molecular Weight |
18.0kDa (163aa) 28-40KDa (SDS-PAGE under reducing conditions.) |
| Amino Acid Sequence | ADPARSEDRY RNPKGSACSR IWQSPRFIAR KRGFTVKMHC YMNSASGNVS WLWKQEMDEN PQQLKLEKGR MEESQNESLA TLTIQGIRFE DNGIYFCQQK CNNTSEVYQG CGTELRVMGF STLAQLKQRN TLKDHHHHHH |
| Tag | His-tag |
| Reactivity | Human |
| Applications | SDS-PAGE |
| Form | Liquid, in Phosphate Buffered Saline (pH 7.4) containing 10% glycerol. |
| Concentration | 0.25mg/ml (determined by Absorbance at 280nm) |
| Purity | > 90% by SDS-PAGE |
| Storage | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -2°C or -7°C. Avoid repeated freezing and thawing cycles. |
| References | Jahn L., et al, (2015) Blood 125:949-958. Yamada S., et al, (2015) Leuk. Lymphoma 56:2141-2145. |
| Background | CD79B, as known as B-cell antigen receptor complex-associated protein beta chain isoform 1, is B-cell-specific glycoprotein B29. It is a single-pass type 1 membrane protein containing one Ig-like V-type domain and one ITAM domain. This protein is required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR). CD79A and B proteins are required for BCR-meditated signaling and consequently for the development and activation of B lineage cells. Recombinant human CD79B, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. |
| Supplier | ARP |
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