| Product Name | CD93, 22-580aa, Human, Baculovirus |
|---|---|
| Description | CD93, also known as complement component C1q receptor, belongs to a family of transmembrane glycoproteins which also includes endosialin and thrombomodulin. It is involved in various aspects of inflammatory reactions. CD93 is expressed by vascular endothelial cells and by a variety of hematopoietic cells. It is receptor for C1q, mannose-binding lectin (MBL2) and pulmonary surfactant protein A (SPA). Recombinant human CD93, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. |
| Synonyms | Complement component C1q receptor , CD93, C1qR(P), C1QR1, C1qRP, CDw93, dJ737E23.1, ECSM3, MXRA4, C1q receptor 1 C1q/MBL/SPA receptor, C1qR, C1qR(p), C1qr1 C1QR1_HUMAN, C1qRp, CD93, CD93 antigen CD93 molecule, CDw93, Complement component 1 q subcomponent receptor 1, Complement component C1q receptor, dJ737E23.1, ECSM3, Matrix remodeling associated protein 4, Matrix remodelling associated 4 Matrix-remodeling-associated protein 4, MXRA4 |
| Host | Virus |
| Molecular Weight | 41.8kDa (360aa) 40-57KDa (SDS-PAGE under reducing conditions) |
| Amino Acid Sequence | TGADTEAVVC VGTACYTAHS GKLSAAEAQN HCNQNGGNLA TVKSKEEAQH VQRVLAQLLR REAALTARMS KFWIGLQREK GKCLDPSLPL KGFSWVGGGE DTPYSNWHKE LRNSCISKRC VSLLLDLSQP LLPSRLPKWS EGPCGSPGSP GSNIEGFVCK FSFKGMCRPL ALGGPGQVTY TTPFQTTSSS LEAVPFASAA NVACGEGDKD ETQSHYFLCK EKAPDVFDWG SSGPLCVSPK YGCNFNNGGC HQDCFEGGDG SFLCGCRPGF RLLDDLVTCA SRNPCSSSPC RGGATCVLGP HGKNYTCRCP QGYQLDSSQL DCVDVDECQD SPCAQECVNT PGGFRCECWV GYEPGGPGEG ACQDVDECAL GRSPCAQGCT NTDGSFHCSC EEGYVLAGED GTQCQDVDEC VGPGGPLCDS LCFNTQGSFH CGCLPGWVLA PNGVSCTMGP VSLGPPSGPP DEEDKGEKEG STVPRAATAS PTRGPEGTPK ATPTTSRPSL SSDAPITSAP LKMLAPSGSP GVWREPSIHH ATAASGPQEP AGGDSSVATQ NNDGTDGQKV EHHHHHH |
| Tag | His-tag |
| Reactivity | Human |
| Applications | SDS-PAGE |
| Form | Liquid, in Phosphate Buffered Saline (pH 7.4) containing 10% glycerol |
| Concentration | 0.5mg/ml (determined by Absorbance at 280nm) |
| Purity | > 90% by SDS-PAGE |
| Storage | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -2°C or -7°C. Avoid repeated freezing and thawing cycles. |
| References | McGreal EP., et al. (2002) J Immunol. 168:5222-5232. Chevrier S., et al. (2009) Proc Natl Acad Sci USA. 106:3895-3900. |
| Background | CD93, also known as complement component C1q receptor, belongs to a family of transmembrane glycoproteins which also includes endosialin and thrombomodulin. It is involved in various aspects of inflammatory reactions. CD93 is expressed by vascular endothelial cells and by a variety of hematopoietic cells. It is receptor for C1q, mannose-binding lectin (MBL2) and pulmonary surfactant protein A (SPA). Recombinant human CD93, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. |
| Supplier | ARP |
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