Product Name | Cdc6 (phospho Ser54) Rabbit Polyclonal Antibody |
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Description | cell division cycle 6(CDC6) Homo sapiens The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks. Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins. [provided by RefSeq, Jul 2008], |
Synonyms | CDC6; CDC18L; Cell division control protein 6 homolog; CDC6-related protein; Cdc18-related protein; HsCdc18; p62(cdc6); HsCDC6 |
Host | Rabbit |
Clonality | Polyclonal |
Conjugate | Unconjugated |
Immunogen | The antiserum was produced against synthesized peptide derived from human CDC6 around the phosphorylation site of Ser54. AA range:20-69 |
Isotype | IgG |
Molecular Weight | 62 |
Reactivity | Monkey, Human, Mouse |
Applications | ELISA, IHC-P, WB |
Diluent Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. |
Concentration | 1 mg/ml |
Storage | Store at -20°C. Avoid repeated freeze-thaw cycles. |
Supplier | ELK Biotechnology |
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