CDK11A/CDK11B Antibody

Category: Antibodies
Catalog
CSB-PA105838
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Product Name CDK11A/CDK11B Antibody
Description Rabbit polyclonal antibody to CDK11B
Synonyms cyclin-dependent kinase 11A/B
Host Rabbit
Clonality Polyclonal
Conjugate Unconjugated
Immunogen Synthetic peptide of human CDK11A/CDK11B
Isotype IgG
Target CDK11A/CDK11B
Reactivity Human, Mouse
Applications ELISA, IHC, WB
Form Liquid
Diluent Buffer -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Uniprot B7ZVY7
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Background Cyclin-dependent kinases (CDKs) are a family of protein kinases first discovered for their role in regulating the cell cycle. They are also involved in regulating transcription, mRNA processing, and the differentiation of nerve cells. They are present in all known eukaryotes, and their regulatory function in the cell cycle has been evolutionarily conserved. CDKs are relatively small proteins, with molecular weights ranging from 34 to 40 kDa, and contain little more than the kinase domain. By definition, a CDK binds a regulatory protein called a cyclin. Without cyclin, CDK has little kinase activity; only the cyclin-CDK complex is an active kinase. CDKs phosphorylate their substrates on serines and threonines, so they are serine-threonine kinases.
Supplier Cusabio

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