C/EBP _ Polyclonal Antibody

Category: Antibodies
Catalog
E-AB-30687
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Product Name C/EBP _ Polyclonal Antibody
Description Important transcriptional activator in the regulation of genes involved in immune and inflammatory responses. Specifically binds to an IL-1 response element in the IL-6 gene. NF-IL6 also binds to regulatory regions of several acute-phase and cytokines genes. It probably plays a role in the regulation of acute-phase reaction, inflammation and hemopoiesis. The consensus recognition site is 5'-T[TG]NNGNAA[TG]-3'. Functions in brown adipose tissue (BAT) differentiation.
Synonyms CEBPB, LAP, TCF5, PP9092, CCAAT/enhancer-binding protein beta, C/EBP beta, Liver activator protein, Nuclear factor NF-IL6, Transcription factor 5, TCF-5
Host Rabbit
Immunogen Synthesized peptide derived from human C/EBP _ around the non-phosphorylation site of Thr235.
Isotype IgG
Reactivity Human, Mouse, Rat
Applications ELISA, IF, IHC, WB
Form PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Uniprot P17676
Background Important transcriptional activator in the regulation of genes involved in immune and inflammatory responses. Specifically binds to an IL-1 response element in the IL-6 gene. NF-IL6 also binds to regulatory regions of several acute-phase and cytokines genes. It probably plays a role in the regulation of acute-phase reaction, inflammation and hemopoiesis. The consensus recognition site is 5'-T[TG]NNGNAA[TG]-3'. Functions in brown adipose tissue (BAT) differentiation.
Supplier Elabscience

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