| Product Name | CEND1, 1-125aa, Human |
|---|---|
| Description | CEND1, as known as BM88, is a neuron-specific protein. It participates in cell cycle control and neuronal differentiation mechanisms during neonatal SVZ neurogenesis and becomes crucial for the transition from neuroblasts to mature neurons when reaching high levels. The similar protein in pig enhances neuroblastoma cell differentiation in vitro and may be involved in neuronal differentiation in vivo. Recombinant human CEND1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. |
| Synonyms | BM88 |
| Host | E. coli |
| Molecular Weight | 13.8kDa (130aa) |
| Amino Acid Sequence | MGSSHHHHHH SSGLVPRGSH MGSMESRGKS ASSPKPDTKV PQVTTEAKVP PAADGKAPLT KPSKKEAPAE KQQPPAAPTT APAKKTSAKA DPALLNNHSN LKPAPTVPSS PDATPEPKGP GDGAEEDEAA SGGPGGRGPW SCENFNPL |
| Tag | His-tag |
| Reactivity | Human |
| Applications | SDS-PAGE |
| Form | Liquid, in 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.4M Urea |
| Concentration | 0.25 mg/ml (determined by Bradford assay) |
| Purity | > 85% by SDS-PAGE |
| Storage | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -2°C or -7°C. Avoid repeated freezing and thawing cycles. |
| References | Makri G. et al. (2010) Stem Cells. 28:127-139 Katsimpardi L. et al. (2008) Stem Cells. 26:1796-1807. |
| Background | CEND1, as known as BM88, is a neuron-specific protein. It participates in cell cycle control and neuronal differentiation mechanisms during neonatal SVZ neurogenesis and becomes crucial for the transition from neuroblasts to mature neurons when reaching high levels. The similar protein in pig enhances neuroblastoma cell differentiation in vitro and may be involved in neuronal differentiation in vivo. Recombinant human CEND1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. |
| Supplier | ARP |
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