CENPS Rabbit Polyclonal Antibody

Category: Antibodies
Catalog
ES10529
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Product Name CENPS Rabbit Polyclonal Antibody
Description centromere protein S(CENPS) Homo sapiens This gene was identified in the neuroblastoma tumor suppressor candidate region on chromosome 1p36. It contains a TFIID-31 domain, similar to that found in TATA box-binding protein-associated factor, TAF(II)31, which is required for p53-mediated transcription activation. This gene was expressed at very low levels in neuroblastoma tumors, and was shown to reduce cell growth in neuroblastoma cells, suggesting that it may have a role in a cell death pathway. The protein is a component of multiple complexes, including the Fanconi anemia (FA) core complex, the APITD1/CENPS complex, and the CENPA-CAD (nucleosome distal) complex. Known functions include an involvement with chromatin associations of the FA core complex, and a role in the stable assembly of the outer kinetochore. Alternative splicing of this gene results in multiple transcript variants. Naturally occurring read-through transcripts also exist
Host Rabbit
Clonality Polyclonal
Conjugate Unconjugated
Immunogen Synthesized peptide derived from human protein . at AA range: 70-150
Isotype IgG
Molecular Weight 15
Reactivity Human
Applications ELISA, WB
Diluent Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Concentration 1 mg/ml
Storage Store at -20°C. Avoid repeated freeze-thaw cycles.
Supplier ELK Biotechnology

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