| Product Name | CEP152 Antibody |
|---|---|
| Description | Rabbit polyclonal antibody to CEP152 |
| Synonyms | Asterless antibody; CE152_HUMAN antibody; Centrosomal protein 152kDa antibody; Centrosomal protein of 152 kDa antibody; Cep152 antibody; FLJ21594 antibody; KIAA0912 antibody; MCPH4 antibody; MCPH9 antibody; Microcephaly primary autosomal recessive 4 antibody; SCKL5 antibody |
| Host | Rabbit |
| Clonality | Polyclonal |
| Conjugate | Unconjugated |
| Immunogen | Synthesized peptide derived from internal of human CEP152. |
| Isotype | IgG |
| Target | CEP152 |
| Reactivity | Human, Mouse |
| Applications | ELISA, IHC |
| Form | liquid |
| Diluent Buffer | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Uniprot | O94986 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Background |
Necessary for centrosome duplication. Acts as a molecular scaffold facilitating the interaction of PLK4 and CENPJ, 2 molecules involved in centriole formation. Also plays a key role in deuterosome-mediated centriole amplification in multiciliated that can generate more than 100 centrioles. Overexpression of CEP152 can drive amplification of centrioles. Nagase T., DNA Res. 5:355-364(1998). The MGC Project Team; Genome Res. 14:2121-2127(2004). Andersen J.S., Nature 426:570-574(2003). |
| Supplier | Cusabio |
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