| Product Name | CGRP (8-37) (human) |
|---|---|
| Description |
CGRP (8-37) (human) is a fragment of calcitonin gene related peptide (CGRP) and is a selective, competetive antagonist of CGRP receptors. CGRP (8-37) (human) acts as a vasodilator agent which is active in vivo and in vitro and can also block pain and migraine headache in animal models. |
| Synonyms | CGRP 8-37 (human), Calcitonin Gene-Related Peptide 8-37 (human), hCGRP-(8-37) |
| Molecular Weight | 3125.64 Da |
| Target | Calcitonin and related receptors |
| Amino Acid Sequence | VTHRLAGLLSRSGGVVKNNFVPTNVGSKAF-NH2 |
| Form | Freeze dried solid |
| Purity | >95% by hplc |
| Cas Number | 119911-68-1 |
| Storage | Store dry, frozen and in the dark |
| Notes | Modifications: C-terminal amide |
| References |
Chiba et al (1989) Calcitonin gene-related peptide receptor antagonist human CGRP-(8-37). Am J Physiol. 256(2 Pt 1) E331 PMID: 2537579Wisskirchen et al (1998) Pharmacological characterization of CGRP receptors mediating relaxation of the rat pulmonary artery and inhibition of twitch responses of the rat vas deferens. Br.J.Pharmacol. 123 1673 PMID: 9605575Hay and Walker (2017) CGRP and its receptors. Headache: The Journal of Head and Face Pain. 57 625 PMID: 28233915 Related areas All peptides >All calcitonin and related receptor modulators >All endocrinology research areas >All cardiovascular research categories >All pain research categories > |
| Supplier | Isca Biochemicals Limited |
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