| Product Name | CHRNA7 Antibody |
|---|---|
| Description | Rabbit polyclonal antibody to CHRFAM7A |
| Synonyms | 7nAChR antibody; a7 nicotinic acetylcholine receptor antibody; acetylcholine receptor; neuronal nicotinic; alpha-7 subunit antibody; ACHA7_HUMAN antibody; AChR antibody; Acra7 antibody; alpha 7 neuronal nicotinic acetylcholine receptor antibody; alpha-7 nicotinic cholinergic receptor subunit antibody; alpha7 antibody; cholinergic receptor; neuronal nicotinic; alpha polypeptide 7 antibody; cholinergic receptor; nicotinic; alpha 7 (neuronal) antibody; cholinergic receptor; nicotinic; alpha 7 antibody; cholinergic receptor; nicotinic; alpha polypeptide 7 antibody; CHRNA7 antibody; CHRNA7-2 antibody; NACHRA7 antibody; neuronal acetylcholine receptor protein; alpha-7 chain antibody; Neuronal acetylcholine receptor subunit alpha-7 antibody |
| Host | Rabbit |
| Clonality | Polyclonal |
| Conjugate | Unconjugated |
| Immunogen | Synthetic peptide of human CHRFAM7A |
| Isotype | IgG |
| Target | CHRNA7 |
| Reactivity | Human, Mouse, Rat |
| Applications | ELISA, IHC, WB |
| Form | Liquid |
| Diluent Buffer | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Uniprot | P36544 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Background | The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The family member CHRNA7, which is located on chromosome 15 in a region associated with several neuropsychiatric disorders, is partially duplicated and forms a hybrid with a novel gene from the family with sequence similarity 7 (FAM7A). Alternative splicing has been observed, and two variants exist, for this hybrid gene. The N-terminally truncated products predicted by the largest open reading frames for each variant would lack the majority of the neurotransmitter-gated ion-channel ligand binding domain but retain the transmembrane region that forms the ion channel. Although current evidence supports transcription of this hybrid gene, translation of the nicotinic acetylcholine receptor-like protein-encoding open reading frames has not been confirmed. |
| Supplier | Cusabio |
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