| Product Name | CK-5/6 Monoclonal Antibody |
|---|---|
| Description | Anti-Cytokeratin 5/6 detects cytokeratins 5 and 6. Cytokeratin 5 is expressed in various epithelia and mesothelial cells, while cytokeratin 6 is expressed by proliferating squamous epithelium. This antibody exhibits a cytoplasmic staining pattern and may be used to aid in the identification of squamous cell carcinoma and in distinguishing malignant mesothelioma from lung adenocarcinomas. The detection of cytokeratin 5 in myoepithelial cells with this antibody may also be used to aid in the determination of breast and prostate malignancies. |
| Synonyms | Keratin, type II cytoskeletal 5 ,58 kDa cytokeratin,Cytokeratin-5,CK-5,Keratin-5,K5,Type-II keratin Kb5,Keratin, type II cytoskeletal 6A,Cytokeratin-6A,CK-6A,Cytokeratin-6D,CK-6D,Keratin-6A,K6A,Type-II keratin Kb6,allergen Hom s 5 |
| Host | Mouse |
| Clone | 6B1 |
| Immunogen | Full length protein from eukaryotic expression system. |
| Isotype | IgG |
| Specificity | This antibody detects endogenous levels of CK-5/6 |
| Reactivity | Human |
| Applications | IHC |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Uniprot | P13647/P02538 |
| Background | Anti-Cytokeratin 5/6 detects cytokeratins 5 and 6. Cytokeratin 5 is expressed in various epithelia and mesothelial cells, while cytokeratin 6 is expressed by proliferating squamous epithelium. This antibody exhibits a cytoplasmic staining pattern and may be used to aid in the identification of squamous cell carcinoma and in distinguishing malignant mesothelioma from lung adenocarcinomas. The detection of cytokeratin 5 in myoepithelial cells with this antibody may also be used to aid in the determination of breast and prostate malignancies. |
| Supplier | Elabscience |
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