| Product Name | CLEC10A, 61-292aa, Human, Baculovirus |
|---|---|
| Description | CLEC10A, also known as C-type lectin domain family 10 member A isoform 2, is a C-type lectin superfamily member 14. It is expressed on immature myeloid dendritic cells and alternatively activated macrophages. This protein roles in regulating adaptive and innate immune responses. Also, it binds in a calcium-dependent manner to terminal galactose and N-acetylgalactosamine, linked to serine or threonine. Recombinant human CLEC10A, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. |
| Synonyms | C-type lectin domain family 10 member A isoform 2, CLEC10A, CD301, CLECSF13, CLECSF14, HML, HML2, MGL |
| Host | Virus |
| Molecular Weight |
70.4kDa (638aa) 70-100kDa (SDS-PAGE under reducing conditions) |
| Amino Acid Sequence | ADPQNSKFQR DLVTLRTDFS NFTSNTVAEI QALTSQGSSL EETIASLKAE VEGFKQERQA VHSEMLLRVQ QLVQDLKKLT CQVATLNNNG EEASTEGTCC PVNWVEHQDS CYWFSHSGMS WAEAEKYCQL KNAHLVVINS REEQNFVQKY LGSAYTWMGL SDPEGAWKWV DGTDYATGFQ NWKPGQPDDW QGHGLGGGED CAHFHPDGRW NDDVCQRPYH WVCEAGLGQT SQESHHHHHH H |
| Tag | His-tag |
| Reactivity | Human |
| Applications | SDS-PAGE |
| Form | Liquid, in Phosphate Buffered Saline (pH 7.4) containing 10% glycerol. |
| Concentration | 0.25mg/ml (determined by Bradford assay) |
| Purity | > 90% by SDS-PAGE |
| Storage | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -2°C or -7°C. Avoid repeated freezing and thawing cycles. |
| References | Lenos K., et al, (2015) Oncotarget 6:26278-26290. Zizzari IG., et al, (2015) PLoS ONE 10:E0132617 |
| Background | CLEC10A, also known as C-type lectin domain family 10 member A isoform 2, is a C-type lectin superfamily member 14. It is expressed on immature myeloid dendritic cells and alternatively activated macrophages. This protein roles in regulating adaptive and innate immune responses. Also, it binds in a calcium-dependent manner to terminal galactose and N-acetylgalactosamine, linked to serine or threonine. Recombinant human CLEC10A, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. |
| Supplier | ARP |
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