| Product Name | CLEC4E Antibody, Biotin conjugated |
|---|---|
| Description | Rabbit polyclonal antibody against CLEC4E conjugated to Biotin |
| Synonyms | C type lectin domain family 4 member E antibody; C type lectin superfamily member 9 antibody; C-type (calcium dependent carbohydrate recognition domain) lectin superfamily member 9 antibody; C-type lectin domain family 4 member E antibody; C-type lectin superfamily member 9 antibody; CLC4E_HUMAN antibody; CLEC 4E antibody; Clec4e antibody; CLECSF9 antibody; Macrophage inducible C type lectin antibody; Macrophage-inducible C-type lectin antibody; MINCLE antibody |
| Host | Rabbit |
| Clonality | Polyclonal |
| Conjugate | Biotin |
| Immunogen | Recombinant human C-type lectin domain family 4 member E protein (41-219AA) |
| Isotype | IgG |
| Target | CLEC4E |
| Reactivity | Human |
| Applications | ELISA |
| Form | Liquid |
| Diluent Buffer | Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Uniprot | Q9ULY5 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Background | C-type lectin that functions as cell-surface receptor for a wide variety of ligands such as damaged cells, fungi and mycobacteria. Plays a role in the recognition of pathogenic fungi, such as Candida albicans. The detection of mycobacteria is via trehalose 6,6'-dimycolate (TDM), a cell wall glycolipid. Specifically recognizes alpha-mannose residues on pathogenic fungi of the genus Malassezia. Recognizes also SAP130, a nuclear protein, that is released by dead or dying cells. Transduces signals through an ITAM-containing adapter protein, Fc receptor gamma chain /FCER1G. Induces secretion of inflammatory cytokines through a pathway that depends on SYK, CARD9 and NF-kappa-B. |
| Supplier | Cusabio |
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