| Product Name | CLEC5A, 28-188aa, Human (Denatured) |
|---|---|
| Description | CLE5CA, also known as C-type lectin superfamily member 5 (CLECSF5) and myeloid DAP12-associating lectin 1 (MDL1), is a C-type lectin. It appears to be a member of a significant myeloid lineage activating pathway. This protein functions as a positive regulator of osteoclastogenesis and regulates inflammatory responses. Recombinant human CLEC5A protein, fused to His-tag at N-terminus, was expressed in E.coli. |
| Synonyms | C-type lectin domain family 5 member A, C-type lectin domain family 5 member A, CLECSF5, MDL-1, MDL1 |
| Host | E. coli |
| Molecular Weight | 49.9 kDa (464aa) |
| Amino Acid Sequence | MGSSHHHHHH SSGLVPRGSH MGSPQIFNKS NDGFTTTRSY GTVSQIFGSS SPSPNGFITT RSYGTVCPKD WEFYQARCFF LSTSESSWNE SRDFCKGKGS TLAIVNTPEK LKFLQDITDA EKYFIGLIYH REEKRWRWIN NSVFNGNVTN QNQNFNCATI GLTKTFDAAS CDISYRRICE KNAK |
| Tag | His-tag |
| Reactivity | Human |
| Applications | SDS-PAGE |
| Form | Liquid, in 20mM phosphate (pH8.0) containing 10% glycerol |
| Concentration | 0.5 mg/ml (determined by Bradford assay) |
| Purity | > 80% by SDS-PAGE |
| Storage | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -2°C or -7°C. Avoid repeated freezing and thawing cycles. |
| References | Bakker AB. et al. (1999) Proc Natl Acad Sci u S A. 96:9792-9796. Chen ST. et al. (2008) Nature. 453:672-676. |
| Background | CLE5CA, also known as C-type lectin superfamily member 5 (CLECSF5) and myeloid DAP12-associating lectin 1 (MDL1), is a C-type lectin. It appears to be a member of a significant myeloid lineage activating pathway. This protein functions as a positive regulator of osteoclastogenesis and regulates inflammatory responses. Recombinant human CLEC5A protein, fused to His-tag at N-terminus, was expressed in E.coli. |
| Supplier | ARP |
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