| Product Name | CNGA1 Antibody |
|---|---|
| Description | Rabbit polyclonal antibody to CNGA1 |
| Synonyms | cGMP gated cation channel alpha 1 antibody; cGMP-gated cation channel alpha-1 antibody; CNCG antibody; CNCG1 antibody; CNG 1 antibody; CNG channel alpha 1 antibody; CNG channel alpha-1 antibody; CNG-1 antibody; CNG1 antibody; Cnga1 antibody; CNGA1_HUMAN antibody; Cyclic nucleotide gated cation channel 1 antibody; Cyclic nucleotide gated channel alpha 1 antibody; Cyclic nucleotide gated channel photoreceptor antibody; Cyclic nucleotide-gated cation channel 1 antibody; Cyclic nucleotide-gated channel alpha-1 antibody; Cyclic nucleotide-gated channel antibody; Interleukin 1 homologue antibody; OTTHUMP00000218675 antibody; OTTHUMP00000223313 antibody; OTTHUMP00000223314 antibody; photoreceptor antibody; RCNC1 antibody; RCNCa antibody; RCNCalpha antibody; Rod photoreceptor cGMP gated channel subunit alpha antibody; Rod photoreceptor cGMP-gated channel subunit alpha antibody; RP49 antibody |
| Host | Rabbit |
| Clonality | Polyclonal |
| Conjugate | Unconjugated |
| Immunogen | Synthesized peptide derived from internal of human CNGA1. |
| Isotype | IgG |
| Target | CNGA1 |
| Reactivity | Human |
| Applications | ELISA, WB |
| Form | liquid |
| Diluent Buffer | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Uniprot | P29973 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Background |
Visual signal transduction is mediated by a G-protein coupled cascade using cGMP as second messenger. This protein can be activated by cyclic GMP which leads to an opening of the cation channel and thereby causing a depolarization of rod photoreceptors. Pittler S.J., J. Biol. Chem. 267:6257-6262(1992). Dhallan R.S., J. Neurosci. 12:3248-3256(1992). Ota T., Nat. Genet. 36:40-45(2004). |
| Supplier | Cusabio |
All Research Products are sold for laboratory RESEARCH USE ONLY and ARE NOT TO BE USED FOR HUMAN OR ANIMAL THERAPEUTIC OR DIAGNOSTIC APPLICATIONS. The information presented is believed to be accurate; however, said information and products are offered without warranty or guarantee since the ultimate conditions of use and the variability of the materials treated are beyond our control. Nothing disclosed herein is to be construed as a recommendation to use our products in violation of any patents. ARP American Research Products, Inc. does not submit its products for regulatory review by any government body or other organization, and we do not validate them for clinical, therapeutic or diagnostic use, or for safety and effectiveness. You are solely responsible for making sure that the way you use the products complies with applicable laws, regulations and governmental policies and for obtaining all necessary approvals, intellectual property rights, licenses and permissions that you may need related to your use. Under no circumstances shall ARP American Research Products, Inc. be liable for damages, whether consequential, compensatory, incidental or special, strict liability or negligence, breach of warranty or any other theory arising out of the use of the products available from ARP American Research Products, Inc. Nothing contained herein warrants that the use of the products will not infringe on the claims of any patents covering the product itself or the use thereof in combination with other products or in the operation of any process. ARP American Research Products, Inc. disclaims any and all representations or warranties of any kind whatsoever, express or implied, including without limitation any implied warranties of merchantability or fitness for a particular purpose, of non-infringement, or regarding results obtained through the use of any product, whether arising from a statute or otherwise in law or from a course of performance, dealing or usage of trade.
