| Product Name | CNTFR Antibody |
|---|---|
| Description | Rabbit polyclonal antibody to CNTFR |
| Synonyms | Ciliary neurotrophic factor receptor alpha antibody; Ciliary neurotrophic factor receptor antibody; Ciliary neurotrophic factor receptor subunit alpha antibody; CNTF Receptor alpha antibody; CNTF receptor subunit alpha antibody; CNTFR Alpha antibody; CNTFR antibody; CNTFR-alpha antibody; CNTFR_HUMAN antibody |
| Host | Rabbit |
| Clonality | Polyclonal |
| Conjugate | Unconjugated |
| Immunogen | Fusion protein corresponding to a region derived from 23-342 amino acids of human ciliary neurotrophic factor receptor |
| Isotype | IgG |
| Target | CNTFR |
| Reactivity | Human, Mouse, Rat |
| Applications | ELISA, WB |
| Form | liquid |
| Diluent Buffer | Supplied at 0.5mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.3, 0.05% sodium azide and 50% glycerol. |
| Uniprot | P26992 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Background |
This gene encodes a member of the type 1 cytokine receptor family. The encoded protein is the ligand-specific component of a tripartite receptor for ciliary neurotrophic factor, which plays a critical role in neuronal cell survival, differentiation and gene expression. Binding of ciliary neurotrophic factor to the encoded protein recruits the transmembrane components of the receptor, gp130 and leukemia inhibitory factor receptor, facilitating signal transduction. Single nucleotide polymorphisms in this gene may be associated with variations in muscle strength, as well as early onset of eating disorders. Alternatively spliced transcript variants have been observed for this gene. |
| Supplier | Cusabio |
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