| Product Name | COL13A1 Polyclonal Antibody |
|---|---|
| Description | COL13A1 (Collagen Type XIII Alpha 1 Chain) is a Protein Coding gene. Diseases associated with COL13A1 include Col13a1-Related Congenital Myasthenic Syndrome and Congenital Myasthenic Syndrome 19. Among its related pathways are Collagen chain trimerization and Phospholipase-C Pathway. GO annotations related to this gene include heparin binding. An important paralog of this gene is COL16A1.This gene encodes the alpha chain of one of the nonfibrillar collagens. The function of this gene product is not known, however, it has been detected at low levels in all connective tissue-producing cells so it may serve a general function in connective tissues. Unlike most of the collagens, which are secreted into the extracellular matrix, collagen XIII contains a transmembrane domain and the protein has been localized to the plasma membrane. The transcripts for this gene undergo complex and extensive splicing involving at least eight exons. Like other collagens, collagen XIII is a trimer; it is not known whether this trimer is composed of one or more than one alpha chain isomer. A number of alternatively spliced transcript variants have been described, but the full length nature of some of them has not been determined. |
| Synonyms | Collagen alpha-1(XIII) chain (COLXIIIA1) |
| Host | Rabbit |
| Immunogen | Synthesized peptide derived from human COL13A1 |
| Isotype | IgG |
| Reactivity | Human, Mouse |
| Applications | ELISA, WB |
| Form | PBS with 0.02% sodium azide,0.5% BSA and 50% glycerol pH 7.4. |
| Uniprot | Q5TAT6 |
| Background | COL13A1 (Collagen Type XIII Alpha 1 Chain) is a Protein Coding gene. Diseases associated with COL13A1 include Col13a1-Related Congenital Myasthenic Syndrome and Congenital Myasthenic Syndrome 19. Among its related pathways are Collagen chain trimerization and Phospholipase-C Pathway. GO annotations related to this gene include heparin binding. An important paralog of this gene is COL16A1.This gene encodes the alpha chain of one of the nonfibrillar collagens. The function of this gene product is not known, however, it has been detected at low levels in all connective tissue-producing cells so it may serve a general function in connective tissues. Unlike most of the collagens, which are secreted into the extracellular matrix, collagen XIII contains a transmembrane domain and the protein has been localized to the plasma membrane. The transcripts for this gene undergo complex and extensive splicing involving at least eight exons. Like other collagens, collagen XIII is a trimer; it is not known whether this trimer is composed of one or more than one alpha chain isomer. A number of alternatively spliced transcript variants have been described, but the full length nature of some of them has not been determined. |
| Supplier | Elabscience |
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