| Product Name | Complement C3 |
|---|---|
| Description | Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. People with C3 deficiency are susceptible to bacterial infection. Immunological Identity and C-3 concentration verified by radial immunodiffusion. Protein determination by the method of Lowry and optical density at 280nm (0.97). electrophoretic and chromatographic data consistant with a molecular weight of approx. 180,000 for this product. Cellulose acetate electrophoresis shows one band with Beta2-mobility. SDS shows one major band. |
| Synonyms | C3, ASP, C3a, C3b, AHUS5, ARMD9, CPAMD1 |
| Form | Purified protein, in 0.01M Sodium phosphate buffer pH 7.2, containing 0.15M NaCl. No preservative. |
| Concentration | 1 mg/ml |
| Purity | 96% by SDS-PAGE |
| Storage | -2°C (aliquot) |
| Notes | Because no test method can offer complete assurance that products derived from human source will not transmit infectious agents, it is recommended that this product be handled with the same precautions used for patient specimens. |
| Background | Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. People with C3 deficiency are susceptible to bacterial infection. |
| Supplier | ARP |
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