| Product Name | Complement factor B Monoclonal Antibody |
|---|---|
| Description | Complement factor B (CFB) is a component of the alternative pathway of complement activation. Complement factor B is cleaved into Ba and Bb by factor D in the presence of C3b. The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes,while Ba inhibits their proliferation. |
| Synonyms | BF,BFD,C3/C5 convertase,CFAB,CFB,Complement factor B,FB,FBI12,GBG,Glycine rich beta glycoprotein,H2 Bf,PBF2,Properdin factor B |
| Host | Mouse |
| Clone | 12 |
| Immunogen | Fusion protein of Complement factor B |
| Isotype | IgM |
| Reactivity | Human |
| Applications | ELISA, IHC, WB |
| Form | PBS with 0.02% sodium azide, 50% glycerol, PH7.3 |
| Uniprot | P00751 |
| Background | Complement factor B (CFB) is a component of the alternative pathway of complement activation. Complement factor B is cleaved into Ba and Bb by factor D in the presence of C3b. The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes,while Ba inhibits their proliferation. |
| Supplier | Elabscience |
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