| Product Name | Bovine Duffy antigen/chemokine receptor (DARC) ELISA Kit |
|---|---|
| Description | Bovine Duffy antigen/chemokine receptor (DARC) ELISA Kit has high sensitivity and excellent specificity for detection of Bovine DARC. No significant cross-reactivity or interference between Bovine DARC and analogues was observed. Duffy antigen/chemokine receptor (DARC) has alternative name : Atypical Chemokine Receptor 1(ACKR1), The protein encoded by this gene is a glycosylated membrane protein and a non-specific receptor for several chemokines. The encoded protein is the receptor for the human malarial parasites Plasmodium vivax and Plasmodium knowlesi. Polymorphisms in this gene are the basis of the Duffy blood group system. Diseases associated with ACKR1 include Malaria and Plasmodium Vivax Malaria. Among its related pathways are Signaling by GPCR and Peptide ligand-binding receptors. GO annotations related to this gene include G-protein coupled receptor activity and transmembrane signaling receptor activity. This Bovine Duffy antigen/chemokine receptor (DARC) ELISA Kit employs a two-site sandwich ELISA to quantitate DARC in samples. An antibody specific for DARC has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyDARC present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for DARC is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of DARC bound in the initial step. The color development is stopped and the intensity of the color is measured. |
| Synonyms | DARC, CTA-134P22.3, CCBP1, CD234, Dfy, FY, GPD, GpFy, WBCQ1, Duffy blood group antigen, Fy glycoprotein, OTTHUMP00000035293, OTTHUMP00000035294, glycoprotein D |
| Method | Sandwich ELISA |
| Detection Range | Please inquire |
| Sensitivity | Please inquire |
| Reactivity | Bovine |
| Sample Types | Cell culture supernatants, Serum, Plasma, Other biological fluids |
| Gene Id | 528076 |
| Storage | 2-8°C |
| Background | Duffy antigen/chemokine receptor (DARC) has alternative name : Atypical Chemokine Receptor 1(ACKR1), The protein encoded by this gene is a glycosylated membrane protein and a non-specific receptor for several chemokines. The encoded protein is the receptor for the human malarial parasites Plasmodium vivax and Plasmodium knowlesi. Polymorphisms in this gene are the basis of the Duffy blood group system. Diseases associated with ACKR1 include Malaria and Plasmodium Vivax Malaria. Among its related pathways are Signaling by GPCR and Peptide ligand-binding receptors. GO annotations related to this gene include G-protein coupled receptor activity and transmembrane signaling receptor activity. |
| Supplier | Abbkine |
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